Nifuratel can be quickly absorbed after oral administration. The peak blood concentration can be reached within 2 hours, and there are reports of high concentrations in saliva and vaginal secretions. The half-life is 2.75 hours. Nifuratel is also very rapidly metabolized, and most of the oral nifuratel is excreted through the kidneys. Together with the two active metabolites, it is excreted in the urine. The original drug and metabolites can also be excreted in milk.