Why CBD Affects Everyone Differently?

Apr 22, 2022

We always say or heard that every people has different reaction on CBD. Some people extremely sensitive, some people even not notice its response. Even some people have opposite reaction compared with most of people. Why?


Your Genetics are the biggest Factor

According to some study, the reaction of people to CBD actually has genetic basis. Your genetic makeup is based on your ancestry across many dozens of generations. some people naturally have more endocannabinoids thanks to an awesome genetic mutation. Endocannabinoids are compounds like THC and CBD that the body produces naturally. When you consume CBD, compounds in the plant take the place of your natural endocannabinoids.

These endocannabinoids are communication molecules make up a larger endocannabinoid system (ECS). This system regulates everything from appetite, cognitive thought, sex drive, and digestion.

This naturally occurring system uptakes CBD and uses it in the neurotransmitters that run throughout your body. But the size and extent of the endocannabinoid system differ from person to person. So those who experience a more noticeable reaction to CBD likely have more endocannabinoid receptors than those who experience a lesser reaction.


Lifestyle Has a Position

Depending on your lifestyle, you may react to the use of CBD differently than others. The two biggest lifestyle factors that shape your response are levels of stress and diet. Your stress levels impact your bodys ability to absorb CBD. For those who are chronically stressed or often feel anxious, youre likely to have a more pronounced reaction to CBD. Thats because CBD is absorbed through our bodys CB2 receptors, the same ones that help us feel relaxed and focused. When taking CBD, you feel more relaxed because it helps to increase the production of serotonin, the chemical that helps create those feelings. However, if you can be described as chill,and generally live a stress-free life, taking CBD wont make you any more relaxed. Like stress, your diet influences your response to CBD. Omega 3 and Omega 6 are the essential fatty acids that your body needs to function properly. These fatty acids affect your bodys endocannabinoid system to take up the CBD compound. Some people have a diet that is low in essential fatty acids. When these individuals take CBD, they react more strongly than those who have a higher concentration of these essential acids in their system.


Your Biological Sex Is a Factor Too

Similar to genetics, your biological sex is also a factor in your response to CBD. That’s because CBD is processed differently in males and females. Typically, females have been found to be more receptive to CBD than males are. The result is that females generally enjoy more of the benefits of CBD. Of course, that doesn’t preclude males from using and benefitting from CBD. They will, however, have to take larger doses of the same product in order to achieve similar results that females experience. The hormonal makeup of females is what makes the difference here. Estrogen naturally interacts with CBD, and this hormone is more common in females than males.


Other Health Concerns Make a Difference

Some people seek out CBD to address a certain health concern, but they find it does not help them in any way. This could be a sign that there is more going in your health than you first realized. If you’re planning on embracing CBD and making it a part of your healthy lifestyle, it’s best to consult with a doctor first. Similarly, if you begin taking CBD as part of your healthcare regimen, and you’re not experiencing the effects you should be, it’s time to visit with your doctor again.


There Are Technical Concerns Too

Of course, on top of all these reasons, there are also user errors to consider. Some users of CBD take the wrong dosage, as there is no “one size fits all” dosage. You may need to experiment with taking small doses, and slowly taking larger doses until you achieve the desired effect. You may not be giving the CBD enough time to take effect. CBD can act quickly for some, but others have to use the products for several weeks before they notice any changes. Finally, you may have bought an inferior product that makes use of a poor quality hemp extract.



Every people is unique, and we all have our own endocannabinoid system. When we seek for healthy lifestyle with CBD, be not too astonished that you are so different with others. Because you are not only have different genetics, endocannabinoid system, also the different lifestyle and body condition. All those may change your CBD way.

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